TY  - JOUR
AU  - Alves da Costa, Thiago
AU  - Peterson, Jacob N
AU  - Lang, Julie
AU  - Shulman, Jeremy
AU  - Liang, Xiayuan
AU  - Freed, Brian M
AU  - Boackle, Susan A
AU  - Lauzurica, Pilar
AU  - Torres, Raul M
AU  - Pelanda, Roberta
PY  - 2021
DO  - 10.1073/pnas.2021570118
UR  - http://hdl.handle.net/20.500.12105/14974
AB  - Central B cell tolerance, the process restricting the development of many newly generated autoreactive B cells, has been intensely investigated in mouse cells while studies in humans have been hampered by the inability to phenotypically distinguish...
LA  - eng
PB  - National Academy of Sciences
KW  - B cell tolerance
KW  - CXCR4
KW  - Autoimmunity
KW  - Hu-mice
KW  - Animals
KW  - Autoantibodies
KW  - Autoantigens
KW  - Autoimmunity
KW  - B-Lymphocytes
KW  - Bone Marrow
KW  - Bone Marrow Cells
KW  - Cell Differentiation
KW  - Central Tolerance
KW  - Female
KW  - Humans
KW  - Immune Tolerance
KW  - Infant, Newborn
KW  - Male
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Transgenic
KW  - Phenotype
KW  - Precursor Cells, B-Lymphoid
KW  - Receptors, Antigen, B-Cell
KW  - Receptors, CXCR4
KW  - Signal Transduction
TI  - Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice
TY  - journal article
ER  -