TY - JOUR AU - Roche-Molina, Marta AU - Hardwick, Bryn AU - Sanchez-Ramos, Cristina AU - Sanz-Rosa, David AU - Gewert, Dirk AU - Cruz, Francisco Miguel AU - Gonzalez-Guerra, Andres AU - Andres, Vicente AU - Palma, Joaquin A AU - Ibáñez, Borja AU - Mckenzie, Grahame AU - Bernal, Juan Antonio PY - 2020 DO - 10.1038/s41598-020-68350-2 UR - http://hdl.handle.net/20.500.12105/11097 AB - N-methyl-2-pyrrolidone (NMP) is a versatile water-miscible polar aprotic solvent. It is used as a drug solubilizer and penetration enhancer in human and animal, yet its bioactivity properties remain elusive. Here, we report that NMP is a bioactive... LA - eng PB - Nature Publishing Group TI - The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis. TY - journal article ER -