TY - JOUR AU - Ortega-Paz, Luis AU - Cristóbal, Helena AU - Ortiz-Perez, José Tomás AU - García de Frutos, Pablo AU - Mendieta, Guiomar AU - Sandoval, Elena AU - Rodriguez, Juan José AU - Ortega, Emilio AU - García-Álvarez, Ana AU - Brugaletta, Salvatore AU - Sabaté, Manel AU - Dantas, Ana Paula PY - 2023 DO - 10.1002/ehf2.14186 UR - http://hdl.handle.net/20.500.12105/16854 AB - AIMSInhibitors of SGLT2 (SGLT2i) have shown a positive impact in patients with chronic heart failure and reduced ejection fraction (HFrEF). Nonetheless, the direct effects of SGLT2i on cardiac cells and how their association with main drugs used for... LA - eng PB - Wiley KW - Heart Failure KW - Humans KW - Spironolactone KW - Matrix Metalloproteinase 9 KW - Sodium-Glucose Transporter 2 KW - Stroke Volume KW - Glycogen Synthase Kinase 3 KW - Interleukin-6 KW - Proto-Oncogene Proteins c-akt KW - Valsartan KW - Fibroblasts KW - Biomarkers TI - Direct actions of dapagliflozin and interactions with LCZ696 and spironolactone on cardiac fibroblasts of patients with heart failure and reduced ejection fraction. TY - journal article ER -