TY - JOUR AU - Iborra, Salvador AU - Izquierdo-Fernandez, Helena Maria AU - Martinez-Lopez, Maria AU - Blanco-Menendez, Noelia AU - Reis e Sousa, Caetano AU - Sancho, David PY - 2012 DO - 10.1172/JCI60660 SN - 0021-9738 UR - http://hdl.handle.net/20.500.12105/9713 AB - In order to prime T cells, DCs integrate signals emanating directly from pathogens and from their noxious action on the host. DNGR-1 (CLEC9A) is a DC-restricted receptor that detects dead cells. Therefore, we investigated the possibility that DNGR-1... LA - eng PB - American Society for Clinical Investigation (ASCI) KW - Adaptive Immunity KW - Animals KW - Antigen Presentation KW - Antigens, Viral KW - Apoptosis KW - CD8-Positive T-Lymphocytes KW - Cells, Cultured KW - Dendritic Cells KW - Gene Knockout Techniques KW - Interferon-gamma TI - The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice TY - journal article ER -