TY  - GEN
AU  - Abas, Sonia
AU  - Rodriguez-Arevalo, Sergio
AU  - Bagan, Andrea
AU  - Grinan-Ferre, Christian
AU  - Vasilopoulou, Foteini
AU  - Brocos-Mosquera, Iria
AU  - Muguruza, Carolina
AU  - Perez, Belen
AU  - Molins, Elies
AU  - Javier Luque, F
AU  - Perez-Lozano, Pilar
AU  - de Jonghe, Steven
AU  - Daelemans, Dirk
AU  - Naesens, Lieve
AU  - Brea, Jose
AU  - Isabel Loza, M
AU  - Hernández-Hernández, Elena
AU  - Garcia-Sevilla, Jesus A
AU  - Julia Garcia-Fuster, M
AU  - Radan, Milica
AU  - Djikic, Teodora
AU  - Nikolic, Katarina
AU  - Pallas, Merce
AU  - Callado, Luis F
AU  - Escolano, Carmen
PY  - 2020
DO  - 10.1021/acs.jmedchem.9b02080
SN  - 0022-2623
UR  - https://hdl.handle.net/20.500.12105/22847
AB  - Imidazoline I-2 receptors (I-2-IR), widely distributed in the CNS and altered in patients that suffer from neurodegenerative disorders, are orphans from a structural point of view, and new I-2-IR ligands are urgently required for improving their...
LA  - eng
PB  - American Chemical Society (ACS)
KW  - Alzheimer Disease
KW  - Molecular Structure
KW  - Organophosphonates
KW  - Quantitative Structure-Activity Relationship
KW  - Hippocampus
KW  - Humans
KW  - Vero Cells
KW  - Chlorocebus aethiops
KW  - HeLa Cells
KW  - Cycloaddition Reaction
KW  - Madin Darby Canine Kidney Cells
KW  - Ligands
KW  - Dogs
KW  - Female
KW  - Animals
KW  - Imidazoles
KW  - Nootropic Agents
KW  - Imidazoline Receptors
KW  - Mice
TI  - Bicyclic alpha-Iminophosphonates as High Affinity Imidazoline I-2 Receptor Ligands for Alzheimer's Disease
TY  - research article
ER  -