TY - THES AU - Victorino Santos, Jesús A3 - Manzanares Fourcade, Miguel PY - 2021 DO - 10.4321/repisalud.12435 UR - http://hdl.handle.net/20.500.12105/12435 AB - The non-coding genome harbors cis-regulatory elements (CRE) that control gene expression in time and space. A tight control of transcription is of great importance, especially during development, and CRE disruption may lead to malformations and other... LA - eng KW - Gene regulation KW - Enhancer KW - Silencer KW - GWAS KW - Atrial fibrillation KW - Atherosclerosis TI - Deciphering regulatory elements as determinants of cardiovascular diseases M3 - doctoral thesis ER -