TY - GEN AU - Urda, Daniel AU - Aragón, Francisco AU - Bautista, Rocío AU - Franco, Leonardo AU - Veredas, Francisco J AU - Claros, Manuel Gonzalo AU - Jerez, José Manuel PY - 2018 DO - 10.1186/s12918-018-0612-8 UR - http://hdl.handle.net/20.500.12105/17642 AB - In RNA-Seq gene expression analysis, a genetic signature or biomarker is defined as a subset of genes that is probably involved in a given complex human trait and usually provide predictive capabilities for that trait. The discovery of new genetic... LA - eng KW - Biological knowledge KW - Biomarkers selection KW - Machine learning KW - Precision medicine KW - RNA-Seq KW - Biomarkers, Tumor KW - Breast Neoplasms KW - Female KW - Gene Expression Profiling KW - Humans KW - Linear Models KW - Machine Learning KW - Precision Medicine KW - Sequence Analysis, RNA TI - BLASSO: integration of biological knowledge into a regularized linear model. TY - research article ER -