TY - JOUR AU - Battles, Michael B AU - Mas-Lloret, Vicente AU - Olmedillas Cela, Eduardo AU - Cano, Olga AU - Vazquez-Alcaraz, Monica AU - Rodriguez, Laura AU - Melero, Jose Antonio AU - McLellan, Jason S PY - 2017 DO - 10.1038/s41467-017-01708-9 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/7181 AB - Human metapneumovirus (hMPV) is a frequent cause of bronchiolitis in young children. Its F glycoprotein mediates virus-cell membrane fusion and is the primary target of neutralizing antibodies. The inability to produce recombinant hMPV F glycoprotein... LA - eng PB - Nature Publishing Group KW - Animals KW - Antibodies, Neutralizing KW - Antibodies, Viral KW - Cercopithecus aethiops KW - Crystallography, X-Ray KW - Female KW - Immunoglobulins, Intravenous KW - Metapneumovirus KW - Mice KW - Mice, Inbred BALB C KW - Protein Domains KW - Protein Engineering KW - Protein Refolding KW - Recombinant Proteins KW - Respiratory Syncytial Virus, Human KW - Vero Cells KW - Viral Fusion Proteins TI - Structure and immunogenicity of pre-fusion-stabilized human metapneumovirus F glycoprotein TY - journal article ER -