TY  - THES
AU  - Sanchez-Lopez, Amanda
A3  - Andres, Vicente
A3  - del Campo, Lara
PY  - 2020
DO  - 10.4321/repisalud.9034
UR  - http://hdl.handle.net/20.500.12105/9034
AB  - Hutchinson-Gilford progeria syndrome (HGPS) is a rare fatal genetic disorder characterized by accelerated aging and premature death at an average age of 14.6 years. “Classical” HGPS is caused by a heterozygous de novo c.1824 C>T dominant synonymous...
LA  - eng
KW  - progeria
KW  - animal model
KW  - gene therapy
KW  - Hutchinson-Gilford
TI  - Generation and characterization of a new conditional mouse model of Hutchinson-Gilford Progeria Syndrome to assess disease progression upon progerin suppression and lamin A restoration
M3  - doctoral thesis
ER  -