TY - JOUR AU - Saiz, Maria Laura AU - Lozano-Chamizo, Laura AU - Florez, Aida Bernardo AU - Marciello, Marzia AU - Diaz-Bulnes, Paula AU - Corte-Iglesias, Viviana AU - Bernet, Cristian Ruiz AU - Rodrigues-Diez, Raul R AU - Martin-Martin, Cristina AU - Rodriguez-Santamaria, Mar AU - Fernandez-Vega, Ivan AU - Rodriguez, Ramon M AU - Diaz-Corte, Carmen AU - Suarez-Alvarez, Beatriz AU - Filice, Marco AU - Lopez-Larrea, Carlos PY - 2024 DO - 10.1016/j.biopha.2024.116492 UR - http://hdl.handle.net/20.500.12105/20070 AB - Targeting epigenetic mechanisms has emerged as a potential therapeutic approach for the treatment of kidney diseases. Specifically, inhibiting the bromodomain and extra-terminal (BET) domain proteins using the small molecule inhibitor JQ1 has shown... LA - eng PB - Elsevier KW - Azepines KW - Reperfusion Injury KW - Triazoles KW - Renal Insufficiency, Chronic KW - Disease Progression KW - Mice, Inbred C57BL KW - Kidney KW - Liposomes KW - Bromodomain Containing Proteins KW - Nuclear Proteins KW - Animals KW - Mice KW - Male KW - Transcription Factors KW - Acute Kidney Injury KW - Disease Models, Animal KW - Nanoparticles KW - Cell Cycle Proteins TI - BET inhibitor nanotherapy halts kidney damage and reduces chronic kidney disease progression after ischemia-reperfusion injury. TY - journal article ER -