TY  - GEN
AU  - Andreu, Inmaculada
AU  - Lence, Emilio
AU  - González-Bello, Concepción
AU  - Mayorga, Cristobalina
AU  - Cuquerella, M Consuelo
AU  - Vayá, Ignacio
AU  - Miranda, Miguel A
PY  - 2020
DO  - 10.3389/fphar.2020.576495
SN  - 1663-9812
UR  - http://hdl.handle.net/20.500.12105/18141
AB  - Lapatinib (LAP) is an anticancer drug generally used to treat breast and lung cancer. It exhibits hypersensitivity reactions in addition to dermatological adverse effects and photosensitivity. Moreover, LAP binds to serum proteins and is readily...
LA  - eng
KW  - Femtosecond transient absorption
KW  - Fluorescence
KW  - Hypersensitivity reactions
KW  - Lapatinib
KW  - Netabolites
KW  - Molecular dynamics simulations
KW  - Protein binding
TI  - Protein Binding of Lapatinib and Its N- and O-Dealkylated Metabolites Interrogated by Fluorescence, Ultrafast Spectroscopy and Molecular Dynamics Simulations.
TY  - research article
ER  -