TY  - GEN
AU  - Tait, Jessica R
AU  - Bilal, Hajira
AU  - Kim, Tae Hwan
AU  - Oh, Abigail
AU  - Peleg, Anton Y
AU  - Boyce, John D
AU  - Oliver, Antonio
AU  - Bergen, Phillip J
AU  - Nation, Roger L
AU  - Landersdorfer, Cornelia B
PY  - 2021
DO  - 10.1016/j.jgar.2021.04.021
SN  - 2213-7165
UR  - https://hdl.handle.net/20.500.12105/23181
AB  - Objectives: Hypermutable Pseudomonas aeruginosa strains are a major challenge in cystic fibrosis. We investigated bacterial killing and resistance emergence for approved ceftazidime and tobramycin regimens, alone and in combination. Methods:...
LA  - eng
PB  - Elsevier
KW  - Pharmacokinetics
KW  - Pharmacodynamics
KW  - Optimised dosing
KW  - Antibiotic combination
KW  - Dynamic in vitro infection model
KW  - Mathematical modelling
KW  - Tobramycin
KW  - Anti-Bacterial Agents
KW  - Microbial Sensitivity Tests
KW  - Ceftazidime
KW  - Humans
KW  - Pseudomonas aeruginosa
TI  - Pharmacodynamics of ceftazidime plus tobramycin combination dosage regimens against hypermutable Pseudomonas aeruginosa isolates at simulated epithelial lining fluid concentrations in a dynamic in vitro infection model
TY  - research article
ER  -