TY  - JOUR
AU  - García-Carpizo, Verónica
AU  - Sarmentero, Jacinto
AU  - Han, Bomie
AU  - Graña Castro, Osvaldo
AU  - Ruiz-Llorente, Sergio
AU  - Pisano, David G
AU  - Serrano Marugan, Manuel
AU  - Brooks, Harold B
AU  - Campbell, Robert M
AU  - Barrero, Maria Jose
PY  - 2016
DO  - 10.1038/srep32952
SN  - 2045-2322
UR  - http://hdl.handle.net/20.500.12105/8572
AB  - The histone methyltransferase NSD2/WHSC1/MMSET is overexpressed in a number of solid tumors but its contribution to the biology of these tumors is not well understood. Here, we describe that NSD2 contributes to the proliferation of a subset of lung...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Azepines
KW  - Benzamides
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Diphenylamine
KW  - Enhancer Elements, Genetic
KW  - Enzyme Inhibitors
KW  - Epigenesis, Genetic
KW  - Gene Expression
KW  - Gene Knockdown Techniques
KW  - Histone-Lysine N-Methyltransferase
KW  - Histones
KW  - Humans
KW  - Lung Neoplasms
KW  - MAP Kinase Kinase Kinases
KW  - Methylation
KW  - Mice
KW  - Mice, Nude
KW  - Nuclear Proteins
KW  - Repressor Proteins
KW  - Transcription Factors
KW  - Transcription, Genetic
KW  - Triazoles
KW  - Xenograft Model Antitumor Assays
KW  - Genes, ras
TI  - NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation
TY  - journal article
ER  -