TY - JOUR AU - Drosten, Matthias AU - Barbacid, Mariano PY - 2022 DO - 10.1002/1878-0261.13168 UR - http://hdl.handle.net/20.500.12105/14702 AB - For decades, KRAS mutant lung adenocarcinomas (LUAD) have been refractory to therapeutic strategies based on personalized medicine owing to the complexity of designing inhibitors to selectively target KRAS and downstream targets with acceptable... LA - eng PB - Wiley KW - genetically engineered mouse tumor models KW - KRAS(G12C) inhibitors KW - lung adenocarcinoma KW - RAF1 KW - RAS signaling KW - tumor resistance KW - Adenocarcinoma of Lung KW - Lung Neoplasms KW - Humans KW - Mutation KW - Oncogenes KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins p21(ras) TI - Targeting KRAS mutant lung cancer: light at the end of the tunnel. TY - journal article ER -