TY  - GEN
AU  - Román-Rodríguez, Francisco José
AU  - Ugalde, Laura
AU  - Álvarez, Lara
AU  - Díez, Begoña
AU  - Ramírez, María José
AU  - Risueño, Cristina
AU  - Cortón, Marta
AU  - Bogliolo, Massimo
AU  - Bernal, Sara
AU  - March, Francesca
AU  - Ayuso, Carmen
AU  - Hanenberg, Helmut
AU  - Sevilla, Julián
AU  - Rodriguez Perales, Sandra
AU  - Torres-Ruiz, Raul
AU  - Surrallés, Jordi
AU  - Bueren, Juan Antonio
AU  - Río, Paula
PY  - 2019
UR  - https://hdl.handle.net/20.500.12105/26146
AB  - Non-homologous end-joining (NHEJ) is the preferred mechanism used by hematopoietic stem cells (HSCs) to repair double-stranded DNA breaks and is particularly increased in cells deficient in the Fanconi anemia (FA) pathway. Here, we show feasible...
LA  - eng
PB  - Cell Press
KW  - CRISPR/Cas9 system
KW  - Fanconi anemia
KW  - gene editing
KW  - hematopoietic stem and progenitor cells
KW  - indels
KW  - non-homologous end-joining
TI  - NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia.
TY  - research article
ER  -