TY - GEN AU - Alharthi, Reem AU - Sueiro-Olivares, Monica AU - Storer, Isabelle AU - Bin Shuraym, Hajer AU - Scott, Jennifer AU - Al-Shidhani, Reem AU - Fortune-Grant, Rachael AU - Bignell, Elaine AU - Tabernero, Lydia AU - Bromley, Michael AU - Zhao, Can AU - Amich, Jorge PY - 2025 DO - 10.1080/21505594.2024.2449075 UR - https://hdl.handle.net/20.500.12105/27645 AB - Sulfur metabolism is an essential aspect of fungal physiology and pathogenicity. Fungal sulfur metabolism comprises anabolic and catabolic routes that are not well conserved in mammals, therefore is considered a promising source of prospective novel... LA - eng PB - Taylor & Francis KW - Aspergillus fumigatus KW - Antifungal targets KW - Fungal virulence KW - Hydroxymethyltransferase KW - In vivo transcriptomics KW - Sulfur metabolism KW - Animals KW - Antifungal Agents KW - Aspergillus fumigatus KW - Cytosol KW - Disease Models, Animal KW - Female KW - Fungal Proteins KW - Gene Expression Profiling KW - Gene Expression Regulation, Fungal KW - Glycine Hydroxymethyltransferase KW - Humans KW - Invasive Pulmonary Aspergillosis KW - Mice KW - Mice, Inbred BALB C KW - Sulfur KW - Virulence TI - The sulfur-related metabolic status of during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target. TY - research article ER -