TY - JOUR AU - de Vasconcelos Júnior, Antônio Alexandre AU - Tirado-Velez, JM AU - Martin-Galiano, Antonio Javier AU - Megías, Diego AU - Ferrandiz-Avellano, Maria-Jose AU - Hernández, Pablo AU - Amblar, Monica AU - de la Campa, Adela G PY - 2023 DO - 10.3390/ijms24065973 UR - http://hdl.handle.net/20.500.12105/16096 AB - The DNA topoisomerases gyrase and topoisomerase I as well as the nucleoid-associated protein HU maintain supercoiling levels in Streptococcus pneumoniae, a main human pathogen. Here, we characterized, for the first time, a topoisomerase I regulator... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - DNA gyrase KW - DNA supercoiling KW - DNA topoisomerase I KW - StaR KW - Nucleoid-associated proteins KW - Supercoiling homeostasis KW - Supercoiling regulation KW - Topsoisomerase regulator KW - DNA Topoisomerases, Type I KW - Streptococcus pneumoniae KW - Humans KW - Novobiocin KW - DNA, Bacterial KW - DNA Gyrase TI - StaR Is a Positive Regulator of Topoisomerase I Activity Involved in Supercoiling Maintenance in Streptococcus pneumoniae TY - journal article ER -