TY - JOUR AU - Asensio Lopez, Maria Del Carmen AU - Lax, Antonio AU - Hernandez Vicente, Alvaro AU - Saura Guillen, Elena AU - Hernandez-Martinez, Antonio AU - Fernandez Del Palacio, Maria Josefa AU - Bayes-Genis, Antoni AU - Pascual-Figal, Domingo A PY - 2020 DO - 10.1038/s41598-020-70454-8 SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/12869 AB - Sodium-glucose co-transporter-2 inhibitors (SGLT2i) have shown to prevent heart failure progression, although the mechanisms remain poorly understood. Here we evaluated the effect of empagliflozin (EMPA, SGLT2i) in cardiac remodeling after myocardial... LA - eng PB - Nature Publishing Group KW - Animals KW - Benzhydryl Compounds KW - Diabetes Mellitus, Experimental KW - GTP Cyclohydrolase KW - Glucosides KW - Male KW - Myocardial Infarction KW - Rats KW - Rats, Wistar KW - Sodium-Glucose Transporter 2 Inhibitors KW - Ventricular Dysfunction, Left KW - Ventricular Remodeling TI - Empagliflozin improves post-infarction cardiac remodeling through GTP enzyme cyclohydrolase 1 and irrespective of diabetes status. TY - journal article ER -