TY  - GEN
AU  - Koelsche, Christian
AU  - Mynarek, Martin
AU  - Schrimpf, Daniel
AU  - Bertero, Luca
AU  - Serrano, Jonathan
AU  - Sahm, Felix
AU  - Reuss, David E
AU  - Hou, Yanghao
AU  - Baumhoer, Daniel
AU  - Vokuhl, Christian
AU  - Flucke, Uta
AU  - Petersen, Iver
AU  - Brück, Wolfgang
AU  - Rutkowski, Stefan
AU  - Zambrano, Sandro Casavilca
AU  - Garcia Leon, Juan Luis
AU  - Diaz Coronado, Rosdali Yesenia
AU  - Gessler, Manfred
AU  - Tirado, Oscar M
AU  - Mora, Jaume
AU  - Alonso, Javier
AU  - García Del Muro, Xavier
AU  - Esteller, Manel
AU  - Sturm, Dominik
AU  - Ecker, Jonas
AU  - Milde, Till
AU  - Pfister, Stefan M
AU  - Korshunov, Andrey
AU  - Snuderl, Matija
AU  - Mechtersheimer, Gunhild
AU  - Schüller, Ulrich
AU  - Jones, David T W
AU  - von Deimling, Andreas
PY  - 2018
DO  - 10.1007/s00401-018-1871-6
SN  - 0001-6322
UR  - http://hdl.handle.net/20.500.12105/11225
AB  - Patients with DICER1 predisposition syndrome have an increased risk to develop pleuropulmonary blastoma, cystic nephroma, embryonal rhabdomyosarcoma, and several other rare tumor entities. In this study, we identified 22 primary intracranial sarcomas,...
LA  - eng
PB  - Springer
KW  - DEAD-box RNA Helicases
KW  - DNA Methylation
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Germ-Line Mutation
KW  - Humans
KW  - Male
KW  - Mutation
KW  - Retrospective Studies
KW  - Rhabdomyosarcoma, Embryonal
KW  - Ribonuclease III
KW  - Sarcoma
TI  - Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.
TY  - research article
ER  -