TY  - JOUR
AU  - Teijeira, Alvaro
AU  - Labiano, Sara
AU  - Garasa, Saray
AU  - Etxeberria, Iñaki
AU  - Santamaría, Eva
AU  - Rouzaut, Ana
AU  - Enamorado, Michel
AU  - Azpilikueta, Arantza
AU  - Inoges, Susana
AU  - Bolaños, Elixabet
AU  - Aznar, Maria Angela
AU  - Sánchez-Paulete, Alfonso R
AU  - Sancho, David
AU  - Melero, Ignacio
PY  - 2018
DO  - 10.1158/2326-6066.CIR-17-0767
UR  - http://hdl.handle.net/20.500.12105/15097
AB  - T and NK lymphocytes express CD137 (4-1BB), a costimulatory receptor of the TNFR family whose function is exploitable for cancer immunotherapy. Mitochondria regulate the function and survival of T lymphocytes. Herein, we show that CD137 costimulation...
LA  - eng
PB  - American Association for Cancer Research (AACR)
KW  - 4-1BB Ligand
KW  - Animals
KW  - Biomarkers
KW  - CD8-Positive T-Lymphocytes
KW  - Cytokines
KW  - Cytotoxicity, Immunologic
KW  - Female
KW  - Gene Silencing
KW  - Humans
KW  - Lymphocytes, Tumor-Infiltrating
KW  - Melanoma, Experimental
KW  - Membrane Potential, Mitochondrial
KW  - Mice
KW  - Mice, Knockout
KW  - Mitochondria
KW  - Neoplasms
KW  - RNA, Small Interfering
KW  - T-Lymphocytes
KW  - Tumor Microenvironment
TI  - Mitochondrial Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation.
TY  - journal article
ER  -