TY  - JOUR
AU  - Bejarano, Leire
AU  - Schuhmacher, Alberto J
AU  - Méndez, Marinela
AU  - Megías, Diego
AU  - Blanco-Aparicio, Carmen
AU  - Martinez, Sonia
AU  - Pastor Fernandez, Joaquin
AU  - Squatrito, Massimo
AU  - Blasco, MA
PY  - 2017
DO  - 10.1016/j.ccell.2017.10.006
UR  - http://hdl.handle.net/20.500.12105/19109
AB  - Glioblastoma multiforme (GBM) is a deadly and common brain tumor. Poor prognosis is linked to high proliferation and cell heterogeneity, including glioma stem cells (GSCs). Telomere genes are frequently mutated. The telomere binding protein TRF1 is...
LA  - eng
PB  - Cell Press
KW  - Disease Models, Animal
KW  - Animals
KW  - Brain Neoplasms
KW  - Cell Line, Tumor
KW  - Disease Progression
KW  - Gene Expression Regulation, Neoplastic
KW  - Glioblastoma
KW  - Humans
KW  - Mice, Knockout
KW  - Mice, Nude
KW  - Neoplastic Stem Cells
KW  - RNA Interference
KW  - Telomere
KW  - Telomeric Repeat Binding Protein 1
KW  - Transplantation, Heterologous
TI  - Inhibition of TRF1 Telomere Protein Impairs Tumor Initiation and Progression in Glioblastoma Mouse Models and Patient-Derived Xenografts.
TY  - journal article
ER  -