TY - JOUR AU - Abad, María AU - Mosteiro, Lluc AU - Pantoja, Cristina AU - Cañamero, Marta AU - Rayon, Teresa AU - Ors, Inmaculada AU - Graña, Osvaldo AU - Megías, Diego AU - Dominguez, Orlando AU - Martinez Garcia, Maria Dolores AU - Manzanares, Miguel AU - Ortega Jimenez, Sagrario AU - Serrano, Manuel PY - 2013 DO - 10.1038/nature12586 UR - http://hdl.handle.net/20.500.12105/17416 AB - Reprogramming of adult cells to generate induced pluripotent stem cells (iPS cells) has opened new therapeutic opportunities; however, little is known about the possibility of in vivo reprogramming within tissues. Here we show that transitory... LA - eng PB - Nature Publishing Group KW - Cellular Reprogramming KW - Animals KW - Blood Cells KW - Cell Dedifferentiation KW - Cell Separation KW - Cells, Cultured KW - Ectoderm KW - Embryoid Bodies KW - Embryonic Stem Cells KW - Female KW - Fibroblasts KW - Gene Expression Profiling KW - Induced Pluripotent Stem Cells KW - Intestines KW - Kidney KW - Kruppel-Like Factor 4 KW - Kruppel-Like Transcription Factors KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Octamer Transcription Factor-3 KW - Organ Specificity KW - Pancreas KW - Proto-Oncogene Proteins c-myc KW - SOXB1 Transcription Factors KW - Stomach KW - Teratoma KW - Totipotent Stem Cells KW - Transcriptome KW - Trophoblasts TI - Reprogramming in vivo produces teratomas and iPS cells with totipotency features. TY - journal article ER -