TY - GEN AU - Garcia-Leon, Juan Antonio AU - Caceres-Palomo, Laura AU - Sanchez-Mejias, Elisabeth AU - Mejias-Ortega, Marina AU - Nuñez-Diaz, Cristina AU - Fernandez-Valenzuela, Juan Jose AU - Sanchez-Varo, Raquel AU - Davila, Jose Carlos AU - Vitorica, Javier AU - Gutierrez, Antonia PY - 2020 DO - 10.3390/ijms21186867 UR - http://hdl.handle.net/20.500.12105/18119 AB - Extracellular amyloid-beta deposition and intraneuronal Tau-laden neurofibrillary tangles are prime features of Alzheimer's disease (AD). The pathology of AD is very complex and still not fully understood, since different neural cell types are... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - Human induced pluripotent stem cells (hiPSCs) KW - Disease modeling KW - Alzheimer’s disease KW - Microglia KW - Astrocytes KW - Oligodendrocytes KW - 3D cultures KW - Brain organoids KW - Células madre pluripotentes inducidas KW - Enfermedad de Alzheimer KW - Microglía KW - Astrocitos KW - Oligodendroglía KW - Organoides KW - Alzheimer Disease KW - Amyloid beta-Peptides KW - Astrocytes KW - Cell Culture Techniques KW - Drug Evaluation, Preclinical KW - Humans KW - Induced Pluripotent Stem Cells KW - Microglia KW - Neural Stem Cells KW - Oligodendroglia KW - Organoids KW - tau Proteins TI - Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease TY - review article ER -