TY - GEN AU - Uccelli, Antonio AU - Laroni, Alice AU - Brundin, Lou AU - Clanet, Michel AU - Fernandez, Oscar AU - Nabavi, Seyed Massood AU - Muraro, Paolo A. AU - Oliveri, Roberto S. AU - Radue, Ernst W. AU - Sellner, Johann AU - Soelberg Sorensen, Per AU - Sormani, Maria Pia AU - Wuerfel, Jens Thomas AU - Battaglia, Mario. A. AU - Freedman, Mark S. PY - 2019 DO - 10.1186/s13063-019-3346-z UR - http://hdl.handle.net/20.500.12105/17864 AB - Background: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system with a degenerative component, leading to irreversible disability. Mesenchymal stem cells (MSC) have been shown to prevent inflammation and neurodegeneration... LA - eng PB - BioMed Central (BMC) KW - Multiple sclerosis KW - Mesenchymal stem cells KW - Mesenchymal stromal cells KW - Clinical trial KW - Esclerosis múltiple KW - Células madre mesenquimatosas KW - Ensayo clínico KW - Adolescent KW - Adult KW - Clinical Trials, Phase I as Topic KW - Clinical Trials, Phase II as Topic KW - Cross-Over Studies KW - Disability Evaluation KW - Double-Blind Method KW - Female KW - Humans KW - Magnetic Resonance Imaging KW - Male KW - Mesenchymal Stem Cell Transplantation KW - Middle Aged KW - Multicenter Studies as Topic KW - Multiple Sclerosis KW - Randomized Controlled Trials as Topic KW - Recovery of Function KW - Time Factors KW - Transplantation, Autologous KW - Treatment Outcome TI - MEsenchymal StEm cells for Multiple Sclerosis (MESEMS): a randomized, double blind, cross-over phase I/II clinical trial with autologous mesenchymal stem cells for the therapy of multiple sclerosis TY - research article ER -