TY - GEN AU - Boughanem, Hatim AU - Cabrera-Mulero, Amanda AU - Hernández-Alonso, Pablo AU - Clemente-Postigo, Mercedes AU - Casanueva, Felipe F AU - Tinahones, Francisco José AU - Morcillo, Sonsoles AU - Crujeiras, Ana B AU - Macias-Gonzalez, Manuel PY - 2020 DO - 10.1186/s13148-020-00875-9 UR - http://hdl.handle.net/20.500.12105/18063 AB - Colorectal cancer (CRC) results from the accumulation of epigenetic and genetic changes in colon cells during neoplasic transformation, which the activation of Wingless (Wnt) signaling pathway is a common mechanism for CRC initiation. The Wnt pathway... LA - eng KW - 25-OH vitamin D KW - Colorectal cancer KW - Neoadjuvant treatment KW - SFRP2 methylation KW - Aged KW - Colorectal Neoplasms KW - DNA Methylation KW - Epigenomics KW - Female KW - HCT116 Cells KW - Humans KW - Intra-Abdominal Fat KW - Leukocytes, Mononuclear KW - Linear Models KW - Male KW - Membrane Proteins KW - Middle Aged KW - Neoadjuvant Therapy KW - Promoter Regions, Genetic KW - Vitamin D KW - Wnt Signaling Pathway TI - Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer. TY - research article ER -