TY  - GEN
AU  - Bussotti, Giovanni
AU  - Gouzelou, Evi
AU  - Côrtes Boité, Mariana
AU  - Kherachi, Ihcen
AU  - Harrat, Zoubir
AU  - Eddaikra, Naouel
AU  - Mottram, Jeremy C
AU  - Antoniou, Maria
AU  - Christodoulou, Vasiliki
AU  - Bali, Aymen
AU  - Guerfali, Fatma Z
AU  - Laouini, Dhafer
AU  - Mukhtar, Maowia
AU  - Dumetz, Franck
AU  - Dujardin, Jean-Claude
AU  - Smirlis, Despina
AU  - Lechat, Pierre
AU  - Pescher, Pascale
AU  - El Hamouchi, Adil
AU  - Lemrani, Meryem
AU  - Chicharro, Carmen
AU  - Llanes-Acevedo, Ivonne Pamela
AU  - Botana, Laura
AU  - Cruz, Israel
AU  - Moreno, Javier
AU  - Jeddi, Fakhri
AU  - Aoun, Karim
AU  - Bouratbine, Aïda
AU  - Cupolillo, Elisa
AU  - Späth, Gerald F
PY  - 2018
DO  - 10.1128/mBio.01399-18
SN  - 2150-7511
UR  - http://hdl.handle.net/20.500.12105/9137
AB  - Protozoan parasites of the genus Leishmania adapt to environmental change through chromosome and gene copy number variations. Only little is known about external or intrinsic factors that govern Leishmania genomic adaptation. Here, by conducting...
LA  - eng
PB  - American Society for Microbiology (ASM)
KW  - Leishmania
KW  - Aneuploidy
KW  - Evolution
KW  - Gene copy number variation
KW  - Genomic adaptation
KW  - Telomeric amplification
KW  - Adaptation, Physiological
KW  - Animals
KW  - Chromosomes
KW  - Cricetinae
KW  - DNA Copy Number Variations
KW  - Dogs
KW  - Evolution, Molecular
KW  - Gene Amplification
KW  - Gene Expression Regulation
KW  - Genes, Protozoan
KW  - Genetic Fitness
KW  - Genomics
KW  - High-Throughput Nucleotide Sequencing
KW  - Humans
KW  - Leishmania donovani
KW  - Leishmaniasis, Visceral
KW  - Telomere
KW  - Gene Dosage
KW  - Genome, Protozoan
KW  - Karyotype
TI  - Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification
TY  - research article
ER  -