TY  - JOUR
AU  - Rivera-Torres, Jose
AU  - Calvo, Conrado J.
AU  - Llach, Anna
AU  - Guzman-Martinez, Gabriela
AU  - Caballero, Ricardo
AU  - Gonzalez-Gomez, Cristina
AU  - Jimenez-Borreguero, Luis J.
AU  - Guadix, Juan A
AU  - Osorio, Fernando G
AU  - López-Otín, Carlos
AU  - Herraiz-Martínez, Adela
AU  - Cabello, Nuria
AU  - Vallmitjana, Alex
AU  - Benítez, Raul
AU  - Gordon, Leslie B
AU  - Jalife, Jose
AU  - Pérez-Pomares, José M
AU  - Tamargo, Juan
AU  - Delpón, Eva
AU  - Hove-Madsen, Leif
AU  - Filgueiras-Rama, David
AU  - Andres, Vicente
PY  - 2016
DO  - 10.1073/pnas.1603754113
SN  - 0027-8424
UR  - http://hdl.handle.net/20.500.12105/7952
AB  - Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disease caused by defective prelamin A processing, leading to nuclear lamina alterations, severe cardiovascular pathology, and premature death. Prelamin A alterations also occur in...
LA  - eng
PB  - National Academy of Sciences
KW  - Hutchinson–Gilford progeria syndrome
KW  - calcium handling
KW  - connexin43
KW  - prelamin A
KW  - progerin
KW  - Adolescent
KW  - Adult
KW  - Animals
KW  - Arrhythmias, Cardiac
KW  - Calcium
KW  - Cardiac Conduction System Disease
KW  - Child
KW  - Child, Preschool
KW  - Connexin 43
KW  - Female
KW  - Heart
KW  - Humans
KW  - Male
KW  - Membrane Proteins
KW  - Metalloendopeptidases
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Myocardium
KW  - Nuclear Lamina
KW  - Progeria
KW  - Sarcoplasmic Reticulum
KW  - Young Adult
TI  - Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations
TY  - journal article
ER  -