TY  - JOUR
AU  - Viswanath, Pavithra
AU  - Radoul, Marina
AU  - Izquierdo-Garcia, Jose L.
AU  - Luchman, Hema Artee
AU  - Gregory Cairncross, J
AU  - Pieper, Russell O
AU  - Phillips, Joanna J
AU  - Ronen, Sabrina M
PY  - 2018
DO  - 10.1186/s40170-018-0178-3
SN  - 2049-3002
UR  - http://hdl.handle.net/20.500.12105/7206
AB  - Background: Magnetic resonance spectroscopy (MRS) studies have identified elevated levels of the phospholipid precursor phosphocholine (PC) and phosphoethanolamine (PE) as metabolic hallmarks of cancer. Unusually, however, PC and PE levels are reduced...
LA  - eng
PB  - BioMed Central (BMC)
KW  - 2-Hydroxyglutarate
KW  - Brain tumors
KW  - Choline kinase
KW  - Ethanolamine kinase
KW  - HIF-1α
KW  - IDH1 mutation
KW  - Magnetic resonance spectroscopy
KW  - Metabolic reprogramming
KW  - Phosphocholine
KW  - Phosphoethanolamine
TI  - Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner
TY  - journal article
ER  -