TY - JOUR AU - Espín, Raquel AU - Roca, Francisco J AU - Candel, Sergio AU - Sepulcre, María P AU - Gonzalez-Rosa, Juan Manuel AU - Alcaraz-Pérez, Francisca AU - Meseguer, José AU - Cayuela, María L AU - Mercader, Nadia AU - Mulero, Victoriano PY - 2013 DO - 10.1242/dmm.010249 UR - http://hdl.handle.net/20.500.12105/10467 AB - Although it is known that tumor necrosis factor receptor (TNFR) signaling plays a crucial role in vascular integrity and homeostasis, the contribution of each receptor to these processes and the signaling pathway involved are still largely unknown.... LA - eng PB - The Company of Biologists KW - Apoptosis KW - Homeostasis KW - Animals KW - Blood Circulation KW - Blood Vessels KW - Caspase 2 KW - Caspase 3 KW - Caspase 8 KW - Caspases KW - Conserved Sequence KW - DNA Fragmentation KW - Embryo, Nonmammalian KW - Endothelial Cells KW - Evolution, Molecular KW - Gene Deletion KW - Humans KW - Models, Biological KW - Receptors, Tumor Necrosis Factor, Type I KW - Signal Transduction KW - Tumor Suppressor Protein p53 KW - Zebrafish TI - TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3. TY - journal article ER -