TY - GEN AU - Torrens-Mas, Margalida AU - Pons, Daniel-Gabriel AU - Sastre-Serra, Jorge AU - Oliver, Jordi AU - Roca, Pilar PY - 2017 DO - 10.1002/jcb.25653 UR - http://hdl.handle.net/20.500.12105/20377 AB - SIRT3, the major deacetylase in mitochondria, plays a crucial role modulating ROS production and scavenging by regulating key proteins implicated in mitochondrial turnover and in antioxidant defenses. Therefore, SIRT3 could confer resistance to... LA - eng PB - Wiley KW - Breast Neoplasms KW - Cisplatin KW - MCF-7 Cells KW - Oxidative Stress KW - Neoplasm Proteins KW - Apoptosis KW - Tamoxifen KW - Female KW - Gene Silencing KW - Reactive Oxygen Species KW - Humans KW - Sirtuin 3 TI - SIRT3 Silencing Sensitizes Breast Cancer Cells to Cytotoxic Treatments Through an Increment in ROS Production TY - research article ER -