TY  - GEN
AU  - Lee, Pamela P
AU  - Lobato-Marquez, Damian
AU  - Pramanik, Nayani
AU  - Sirianni, Andrea
AU  - Daza-Cajigal, Vanessa
AU  - Rivers, Elizabeth
AU  - Cavazza, Alessia
AU  - Bouma, Gerben
AU  - Moulding, Dale
AU  - Hultenby, Kjell
AU  - Westerberg, Lisa S
AU  - Hollinshead, Michael
AU  - Lau, Yu-Lung
AU  - Burns, Siobhan O
AU  - Mostowy, Serge
AU  - Bajaj-Elliott, Mona
AU  - Thrasher, Adrian J
PY  - 2017
DO  - 10.1038/s41467-017-01676-0
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/20463
AB  - Dysregulation of autophagy and inflammasome activity contributes to the development of auto-inflammatory diseases. Emerging evidence highlights the importance of the actin cytoskeleton in modulating inflammatory responses. Here we show that deficiency...
LA  - eng
PB  - Nature Publishing Group
KW  - Wiskott-Aldrich Syndrome Protein
KW  - Enteropathogenic Escherichia coli
KW  - Dendritic Cells
KW  - Bacterial Load
KW  - Humans
KW  - THP-1 Cells
KW  - Cell Line, Tumor
KW  - Mice, Inbred C57BL
KW  - Actin Cytoskeleton
KW  - Autophagy
KW  - Immunity, Innate
KW  - Wiskott-Aldrich Syndrome
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Monocytes
KW  - Nigericin
KW  - Toll-Like Receptor 4
KW  - Septins
KW  - Interferon Type I
KW  - Animals
KW  - Inflammasomes
KW  - Mice, Knockout
KW  - Shigella flexneri
KW  - Mice
TI  - Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells
TY  - research article
ER  -