TY - GEN AU - Amarilla-Quintana, Sandra AU - Navarro, Paloma AU - Hernández Martínez, Iván AU - Ramos, Alejandra AU - Montero-Calle, Ana Maria AU - Cabezas-Sainz, Pablo AU - Barrero, Maria AU - Megias Vazquez, Diego AU - Vilaplana-Marti, Borja AU - Epifano, Carolina AU - Gomez-Dominguez, Deborah AU - Monzon-Fernandez, Sara AU - Cuesta de la Plaza, Isabel AU - Sánchez, Laura AU - Barderas Manchado, Rodrigo AU - Garcia-Donas, Jesus AU - Martin, Alberto AU - Perez de Castro, Ignacio PY - 2025 DO - 10.1002/1878-0261.13799 SN - 1574-7891 UR - https://hdl.handle.net/20.500.12105/26000 AB - Forkhead box L2 (FOXL2) encodes a transcription factor essential for sex determination, and ovary development and maintenance. Mutations in this gene are implicated in syndromes involving premature ovarian failure and granulosa cell tumors (GCTs).... LA - eng PB - Wiley KW - CRISPR KW - FOXL2 KW - Granulosa cell tumor KW - Rare cancer TI - CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds TY - research article ER -