TY  - JOUR
AU  - Forés, Marta
AU  - Simón-Carrasco, Lucía
AU  - Ajuria, Leiore
AU  - Samper, Núria
AU  - González-Crespo, Sergio
AU  - Drosten, Matthias
AU  - Jiménez, Gerardo
AU  - Barbacid, Mariano
PY  - 2017
DO  - 10.1371/journal.pgen.1006622
SN  - 1553-7404
UR  - http://hdl.handle.net/20.500.12105/7232
AB  - HMG-box proteins, including Sox/SRY (Sox) and TCF/LEF1 (TCF) family members, bind DNA via their HMG-box. This binding, however, is relatively weak and both Sox and TCF factors employ distinct mechanisms for enhancing their affinity and specificity for...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Amino Acid Motifs
KW  - Amino Acid Sequence
KW  - Animals
KW  - Animals, Genetically Modified
KW  - Base Sequence
KW  - Binding Sites
KW  - DNA
KW  - Drosophila
KW  - Drosophila Proteins
KW  - Embryo, Nonmammalian
KW  - HEK293 Cells
KW  - HMG-Box Domains
KW  - HMGB Proteins
KW  - High Mobility Group Proteins
KW  - Homeodomain Proteins
KW  - Humans
KW  - Immunohistochemistry
KW  - Microscopy, Confocal
KW  - Models, Genetic
KW  - Neoplasms
KW  - Protein Binding
KW  - Repressor Proteins
KW  - Sequence Homology, Amino Acid
KW  - Sequence Homology, Nucleic Acid
KW  - Mutation
TI  - A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer
TY  - journal article
ER  -