TY  - JOUR
AU  - Natrajan, Muktha S
AU  - de la Fuente, Alerie G
AU  - Crawford, Abbe H
AU  - Linehan, Eimear
AU  - Nuñez, Vanessa
AU  - Johnson, Kory R
AU  - Wu, Tianxia
AU  - Fitzgerald, Denise C
AU  - Ricote, Mercedes
AU  - Bielekova, Bibiana
AU  - Franklin, Robin J M
AU  - Natrajan, Muktha S.
AU  - de la Fuente, Alerie G.
AU  - Crawford, Abbe H.
AU  - Johnson, Kory R.
AU  - Fitzgerald, Denise C.
AU  - Franklin, Robin J. M.
PY  - 2015
DO  - 10.1093/brain/awv289
SN  - 0006-8950
UR  - http://hdl.handle.net/20.500.12105/15147
AB  - The efficiency of central nervous system remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In...
LA  - eng
PB  - Oxford University Press
KW  - Phagocytosis
KW  - Adult
KW  - Aging
KW  - Animals
KW  - Benzoates
KW  - Bexarotene
KW  - Biphenyl Compounds
KW  - Female
KW  - Humans
KW  - Macrophages
KW  - Male
KW  - Mice
KW  - Mice, Knockout
KW  - Middle Aged
KW  - Monocytes
KW  - Multiple Sclerosis
KW  - Myelin Sheath
KW  - Retinoid X Receptor alpha
KW  - Signal Transduction
KW  - Tetrahydronaphthalenes
KW  - Transcriptome
KW  - Young Adult
TI  - Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.
TY  - journal article
ER  -