TY - JOUR AU - Martinez Rodriguez, Paula AU - Blasco , MA PY - 2017 DO - 10.1083/jcb.201610111 SN - 0021-9525 UR - http://hdl.handle.net/20.500.12105/8470 AB - Telomeres, the protective ends of linear chromosomes, shorten throughout an individual's lifetime. Telomere shortening is proposed to be a primary molecular cause of aging. Short telomeres block the proliferative capacity of stem cells, affecting... LA - eng PB - Rockefeller University Press KW - Aging KW - Animals KW - Cell Transformation, Neoplastic KW - Chromosomal Instability KW - Dyskeratosis Congenita KW - Fetal Growth Retardation KW - Humans KW - Intellectual Disability KW - Microcephaly KW - Molecular Targeted Therapy KW - Mutation KW - Neoplasms KW - Telomerase KW - Telomere KW - Telomere Homeostasis KW - Telomere Shortening TI - Telomere-driven diseases and telomere-targeting therapies TY - journal article ER -