TY - GEN AU - Schwentner, Raphaela AU - Herrero-Martin, David AU - Kauer, Maximilian O AU - Mutz, Cornelia N AU - Katschnig, Anna M AU - Sienski, Grzegorz AU - Alonso, Javier AU - Aryee, Dave N T AU - Kovar, Heinrich PY - 2017 DO - 10.18632/oncotarget.14091 SN - 1949-2553 UR - http://hdl.handle.net/20.500.12105/9614 AB - MicroRNAs serve to fine-tune gene expression and play an important regulatory role in tissue specific gene networks. The identification and validation of miRNA target genes in a tissue still poses a significant problem since the presence of a seed... LA - eng PB - Impact Journals KW - EWS-FLI1 KW - Ewing sarcoma KW - PAR-CLIP KW - TGFB/BMP pathway KW - miR-17-92 KW - 3' Untranslated Regions KW - Bone Morphogenetic Proteins KW - Cell Line, Tumor KW - Gene Expression Profiling KW - Genetic Predisposition to Disease KW - Humans KW - MicroRNAs KW - Mutation KW - Oligonucleotide Array Sequence Analysis KW - Oncogene Proteins, Fusion KW - Proto-Oncogene Protein c-fli-1 KW - RNA-Binding Protein EWS KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sarcoma, Ewing KW - Sequence Analysis, RNA KW - Signal Transduction KW - Transforming Growth Factor beta KW - Gene Expression Regulation, Neoplastic TI - The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma TY - research article ER -