TY - GEN AU - Martini, Alessandra Cadete AU - Gomez-Arboledas, Angela AU - Forner, Stefania AU - Rodriguez-Ortiz, Carlos J AU - McQuade, Amanda AU - Danhash, Emma AU - Phan, Jimmy AU - Javonillo, Dominic AU - Ha, Jordan-Vu AU - Tram, Melanie AU - Trujillo-Estrada, Laura AU - da Cunha, Celia AU - Ager, Rahasson R AU - Davila, Jose C AU - Kitazawa, Masashi AU - Blurton-Jones, Mathew AU - Gutierrez, Antonia AU - Baglietto-Vargas, David AU - Medeiros, Rodrigo AU - LaFerla, Frank M PY - 2019 DO - 10.1073/pnas.1914088116 UR - http://hdl.handle.net/20.500.12105/17915 AB - Defects in interleukin-1β (IL-1β)-mediated cellular responses contribute to Alzheimer's disease (AD). To decipher the mechanism associated with its pathogenesis, we investigated the molecular events associated with the termination of IL-1β... LA - eng KW - 3xTg-AD KW - Alzheimer’s disease KW - IL-1R1 KW - TOM1 KW - Target of Myb1 TI - Amyloid-beta impairs TOM1-mediated IL-1R1 signaling. TY - research article ER -