TY - GEN AU - Corral, María J AU - Benito-Peña, Elena AU - Jiménez-Antón, M Dolores AU - Cuevas, Laureano AU - Moreno-Bondi, María C AU - Alunda, José M PY - 2016 DO - 10.1371/journal.pntd.0004525 SN - 1935-2735 UR - http://hdl.handle.net/20.500.12105/6845 AB - BACKGROUND: Allicin has shown antileishmanial activity in vitro and in vivo. However the mechanism of action underlying its antiproliferative effect against Leishmania has been virtually unexplored. In this paper, we present the results obtained in... LA - eng PB - Public Library of Science (PLOS) KW - Adenosine Triphosphate KW - Apoptosis KW - Calcium KW - Dose-Response Relationship, Drug KW - Leishmania KW - Membrane Potential, Mitochondrial KW - Mitochondria KW - Reactive Oxygen Species KW - Sulfinic Acids TI - Allicin Induces Calcium and Mitochondrial Dysregulation Causing Necrotic Death in Leishmania TY - research article ER -