TY - JOUR AU - Salido-Medina, Ana B AU - Gil, Aritz AU - Expósito, Víctor AU - Martínez, Fernando AU - Redondo, Juan M AU - Hurlé, María A AU - Nistal, J Francisco AU - García, Raquel PY - 2022 DO - 10.1016/j.biopha.2022.112910 UR - http://hdl.handle.net/20.500.12105/15730 AB - Aortic stenosis (AS) exposes the left ventricle (LV) to pressure overload leading to detrimental LV remodeling and heart failure. In animal models of cardiac injury or hemodynamic stress, bone morphogenetic protein-7 (BMP7) protects LV against... LA - eng PB - Elsevier KW - Aortic Valve Stenosis KW - Heart Ventricles KW - Animals KW - Bone Morphogenetic Protein 7 KW - Bone Morphogenetic Protein Receptors KW - Bone Morphogenetic Protein Receptors, Type I KW - Disease Models, Animal KW - Fibrosis KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Molecular Docking Simulation KW - Myocytes, Cardiac KW - Ventricular Remodeling TI - BMP7-based peptide agonists of BMPR1A protect the left ventricle against pathological remodeling induced by pressure overload. TY - journal article ER -