TY - JOUR AU - Fisher, Jacob S AU - Adán-Barrientos, Irene AU - Kumar, Naveen R AU - Lancaster, Jessica N PY - 2024 DO - 10.1111/acel.14140 UR - http://hdl.handle.net/20.500.12105/20209 AB - Weakened germinal center responses by the aged immune system result in diminished immunity against pathogens and reduced efficacy of vaccines. Prolonged contacts between activated B cells and CD4+ T cells are crucial to germinal center formation and T... LA - eng PB - Wiley KW - CD40 Ligand KW - Cell Differentiation KW - Proto-Oncogene Proteins c-bcl-6 KW - Animals KW - Mice KW - Aging KW - Cellular Microenvironment KW - Germinal Center KW - Mice, Inbred C57BL KW - T Follicular Helper Cells KW - T-Lymphocytes, Helper-Inducer KW - Male KW - Female TI - The aged microenvironment impairs BCL6 and CD40L induction in CD4+ T follicular helper cell differentiation. TY - journal article ER -