TY - GEN AU - Meyer-Berg, Helena AU - Zhou Yang, Lucia AU - de Lucas, Maria Pilar AU - Zambrano, Alberto AU - Hyde, Stephen C AU - Gill, Deborah R PY - 2020 DO - 10.1186/s13287-020-01950-x UR - http://hdl.handle.net/20.500.12105/11768 AB - Gene therapy is being investigated for a range of serious lung diseases, such as cystic fibrosis and emphysema. Recombinant adeno-associated virus (rAAV) is a well-established, safe, viral vector for gene delivery with multiple naturally occurring and... LA - eng PB - BioMed Central (BMC) KW - AAV capsids KW - AAV serotypes KW - Alveolar type II cells KW - Gene therapy KW - Human embryonic stem cells KW - Lung organoids KW - rAAV KW - Stem cell-based tissue model KW - Viral infection model KW - Cell Line KW - Dependovirus KW - Gene Transfer Techniques KW - Genetic Therapy KW - Genetic Vectors KW - Human Embryonic Stem Cells KW - Humans KW - Lung KW - Lung Diseases KW - Models, Biological KW - Organoids KW - Parenchymal Tissue TI - Identification of AAV serotypes for lung gene therapy in human embryonic stem cell-derived lung organoids TY - research article ER -