TY - JOUR AU - Sánchez-Ramos, Cristina AU - Prieto, Ignacio AU - Tierrez, Alberto AU - Laso, Javier AU - Valdecantos, M Pilar AU - Bartrons, Ramon AU - Roselló-Catafau, Joan AU - Monsalve, María PY - 2017 DO - 10.1089/ars.2016.6836 UR - http://hdl.handle.net/20.500.12105/17394 AB - AIMSLiver steatosis is associated with mitochondrial dysfunction and elevated reactive oxygen species (ROS) levels together with enhanced sensitivity to ischemia-reperfusion (IR) injury and limited response to preconditioning protocols. Here, we... LA - eng PB - Mary Ann Liebert KW - Down-Regulation KW - Animals KW - Antioxidants KW - Cells, Cultured KW - Disease Models, Animal KW - Fatty Liver KW - Gene Knockout Techniques KW - Hepatocytes KW - Ischemic Preconditioning KW - Liver KW - Mice KW - Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha KW - Reactive Oxygen Species KW - Reperfusion Injury TI - PGC-1α Downregulation in Steatotic Liver Enhances Ischemia-Reperfusion Injury and Impairs Ischemic Preconditioning. TY - journal article ER -