TY - GEN AU - Segura-Collar, Berta AU - Gargini, Ricardo AU - Tovar-Ambel, Elena AU - Hernandez-SanMiguel, Esther AU - Epifano, Carolina AU - Perez de Castro, Ignacio AU - Hernández-Laín, Aurelio AU - Casas-Tinto, Sergio AU - Sánchez-Gómez, Pilar PY - 2020 DO - 10.3390/cancers12010208 SN - 2072-6694 UR - http://hdl.handle.net/20.500.12105/9083 AB - Despite the high frequency of EGFR and TP53 genetic alterations in gliomas, little is known about their crosstalk during tumor progression. Here, we described a mutually exclusive distribution between mutations in these two genes. We found that... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - EGFR/AKT signaling KW - Autophagy KW - Glioma KW - Mutant p53 KW - Vesicular trafficking KW - Wild-type p53 TI - The EGFR-TMEM167A-p53 Axis Defines the Aggressiveness of Gliomas TY - research article ER -