TY - GEN AU - de Diego-Otero, Yolanda AU - Calvo-Medina, Rocio AU - Quintero-Navarro, Carolina AU - Sánchez-Salido, Lourdes AU - García-Guirado, Francisco AU - del Arco-Herrera, Ignacio AU - Fernández-Carvajal, Isabel AU - Ferrando-Lucas, Teresa AU - Caballero-Andaluz, Rafaela AU - Pérez-Costillas, Lucia PY - 2014 DO - 10.1186/1745-6215-15-345 UR - http://hdl.handle.net/20.500.12105/17075 AB - BACKGROUND: Fragile X syndrome (FXS) is an inherited neurodevelopmental condition characterised by behavioural, learning disabilities, physical and neurological symptoms. In addition, an important degree of comorbidity with autism is also present.... LA - eng PB - BioMed Central (BMC) KW - Antioxidants KW - Experimental treatment KW - Fragile X syndrome KW - Oxidative stress KW - Trial KW - Síndrome del cromosoma X frágil KW - Ácido ascórbico KW - Alfa-tocoferol KW - España KW - Resultado del tratamiento KW - Masculino KW - Adolescent Behavior KW - Adolescent Development KW - Antioxidants KW - Antioxidants KW - Biological Markers KW - Checklist KW - Child KW - Child Behavior KW - Child Development KW - Clinical Protocols KW - Cognition KW - Drug Combinations KW - Fragile X Syndrome KW - Humans KW - Male KW - Pilot Projects KW - Research Design KW - Spain KW - Time Factors KW - Treatment Outcome KW - Wechsler Scales KW - alpha-Tocopherol KW - Adolescent TI - A combination of ascorbic acid and α-tocopherol to test the effectiveness and safety in the fragile X syndrome: study protocol for a phase II, randomized, placebo-controlled trial. TY - research article ER -