TY - JOUR AU - Serna, Marina PY - 2019 DO - 10.3389/fmolb.2019.00033 SN - 2296-889X UR - http://hdl.handle.net/20.500.12105/7830 AB - Electron microscopy of frozen hydrated samples (cryo-EM) is a powerful structural technique that allows the direct study of functional macromolecular complexes in an almost physiological environment. Protein macromolecular complexes are dynamic... LA - eng PB - Frontiers Media KW - Cryo-electron microscopy KW - Heterogeneity KW - Macromolecular complexes KW - Psuedosymmetry KW - Refinement KW - Resolution KW - Single particle processing TI - Hands on Methods for High Resolution Cryo-Electron Microscopy Structures of Heterogeneous Macromolecular Complexes TY - journal article ER -