TY - JOUR AU - Wong, Jasmine C AU - Perez-Mancera, Pedro A AU - Huang, Tannie Q AU - Kim, Jangkyung AU - Grego-Bessa, Joaquim AU - Del Pilar Alzamora, Maria AU - Kogan, Scott C AU - Sharir, Amnon AU - Keefe, Susan H AU - Morales, Carolina E AU - Schanze, Denny AU - Castel, Pau AU - Hirose, Kentaro AU - Huang, Guo N AU - Zenker, Martin AU - Sheppard, Dean AU - Klein, Ophir D AU - Tuveson, David A AU - Braun, Benjamin S AU - Shannon, Kevin PY - 2020 DO - 10.1172/jci.insight.140495 SN - 2379-3708 UR - http://hdl.handle.net/20.500.12105/12562 AB - Somatic KRAS mutations are highly prevalent in many cancers. In addition, a distinct spectrum of germline KRAS mutations causes developmental disorders called RASopathies. The mutant proteins encoded by these germline KRAS mutations are less... LA - eng PB - American Society for Clinical Investigation (ASCI) TI - KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice. TY - journal article ER -