TY - GEN AU - Hsieh, Ching-Lin AU - Rush, Scott A AU - Palomo-Sanz, Concepcion AU - Chou, Chia-Wei AU - Pickens, Whitney AU - Mas-Lloret, Vicente AU - McLellan, Jason S PY - 2022 DO - 10.1038/s41467-022-28931-3 UR - http://hdl.handle.net/20.500.12105/14467 AB - The human metapneumovirus (hMPV) fusion (F) protein is essential for viral entry and is a key target of neutralizing antibodies and vaccine development. The prefusion conformation is thought to be the optimal vaccine antigen, but previously described... LA - eng PB - Nature Publishing Group KW - Protein vaccines KW - Virology KW - X-ray crystallography TI - Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins TY - research article ER -