TY - GEN AU - Musteanu, Mónica AU - Blaas, Leander AU - Zenz, Rainer AU - Svinka, Jasmin AU - Hoffmann, Thomas AU - Grabner, Beatrice AU - Schramek, Daniel AU - Kantner, Hans-Peter AU - Müller, Mathias AU - Kolbe, Thomas AU - Rülicke, Thomas AU - Moriggl, Richard AU - Kenner, Lukas AU - Stoiber, Dagmar AU - Penninger, Josef Martin AU - Popper, Helmut AU - Casanova, Emilio AU - Eferl, Robert PY - 2012 UR - https://hdl.handle.net/20.500.12105/26794 AB - We here establish a mouse cancer model called Multi-Hit that allows for the evaluation of oncogene cooperativities in tumor development. The model is based on the stochastic expression of oncogene combinations ('hits') that are mediated by Cre in a... LA - eng PB - Springuer Nature KW - oncogenic RAS KW - CELL KW - RECOMBINATION KW - ACTIVATION TI - A mouse model to identify cooperating signaling pathways in cancer. TY - research article ER -