TY  - JOUR
AU  - Callen, Elsa
AU  - Zong, Dali
AU  - Wu, Wei
AU  - Wong, Nancy
AU  - Stanlie, Andre
AU  - Ishikawa, Momoko
AU  - Pavani, Raphael
AU  - Dumitrache, Lavinia C
AU  - Byrum, Andrea K
AU  - Mendez-Dorantes, Carlos
AU  - Martinez, Paula
AU  - Canela, Andres
AU  - Maman, Yaakov
AU  - Day, Amanda
AU  - Kruhlak, Michael J
AU  - Blasco, MA
AU  - Stark, Jeremy M
AU  - Mosammaparast, Nima
AU  - McKinnon, Peter J
AU  - Nussenzweig, André
PY  - 2020
DO  - 10.1016/j.molcel.2019.09.024
UR  - http://hdl.handle.net/20.500.12105/18185
AB  - 53BP1 activity drives genome instability and lethality in BRCA1-deficient mice by inhibiting homologous recombination (HR). The anti-recombinogenic functions of 53BP1 require phosphorylation-dependent interactions with PTIP and RIF1/shieldin effector...
LA  - eng
PB  - Cell Press
KW  - Aging
KW  - Animals
KW  - BRCA1 Protein
KW  - DNA Breaks, Double-Stranded
KW  - DNA Damage
KW  - Genomic Instability
KW  - Homologous Recombination
KW  - Mice
KW  - Mutation
KW  - Poly(ADP-ribose) Polymerase Inhibitors
KW  - Rad51 Recombinase
KW  - Tumor Suppressor p53-Binding Protein 1
KW  - Ubiquitin-Protein Ligases
TI  - 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
TY  - journal article
ER  -