TY - JOUR AU - Djurec, Magdolna AU - Graña Castro, Osvaldo AU - Lee, Albert AU - Troulé, Kevin AU - Espinet, Elisa AU - Cabras, Lavinia AU - Navas, Carolina AU - Blasco, María Teresa AU - Martín-Díaz, Laura AU - Burdiel, Miranda AU - Li, Jing AU - Liu, Zhaoqi AU - Vallespinós, Mireia AU - Sanchez-Bueno, Francisco AU - Sprick, Martin R AU - Trumpp, Andreas AU - Sainz, Bruno AU - Al-Shahrour, Fatima AU - Rabadan, Raul AU - Guerra, Carmen AU - Barbacid, Mariano PY - 2018 DO - 10.1073/pnas.1717802115 SN - 0027-8424 UR - http://hdl.handle.net/20.500.12105/8305 AB - Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of abundant desmoplastic stroma primarily composed of cancer-associated fibroblasts (CAFs). It is generally accepted that CAFs stimulate tumor progression and might be implicated... LA - eng PB - National Academy of Sciences KW - CAFs KW - PDAC KW - Saa3 KW - mouse models KW - stroma KW - Animals KW - Cancer-Associated Fibroblasts KW - Carcinoma, Pancreatic Ductal KW - Cell Movement KW - Cell Proliferation KW - Female KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Pancreas KW - Pancreatic Neoplasms KW - Serum Amyloid A Protein KW - Stromal Cells KW - Tumor Microenvironment TI - Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors TY - journal article ER -